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Pramipexole Dihydrochloride

Pramipexole Dihydrochloride treat Parkinsonism
Categories: Pharmaceutical Chemicals.
Synonyms: Pramipexole; Pramipexole Dihydrochloride; Pramipexole HCL; Pramipexole Hydrochloride; Dihydrochloride

CAS:104632-25-9
MF: C10H19Cl2N3S
MW:284.25
Chemical Properties: White Crystalline Powder
INQUIRY
Description
Pramipexole hydrochloride is a kind of drugs for treatment of Parkinson syndrome. 

Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

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