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Tetracaine Hydrochloride

Synonyms: Tetracaine HCl, Amethocaine hydrochloride, Anethaine, Butethanol, Curtacain, Decicain, Gingicain M, Menonasal, Pantocaine, Pontocaine hydrochloride, Tetracaine hydrochloride, Tonexol, local anesthetic

CAS No.: 136-47-0
Molecular formula: C15H25ClN2O2
Nolecular weight: 300.82
EINECS: 205-248-5
Appearance: Fine white crystalline and odorless powder
Assay: 99%min.
Tetracaine (INN, also known as amethocaine; Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

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